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The key symptoms of PFAPA are those in its name: periodic high fever at intervals of about 3–5 weeks, as well as aphthous ulcers, pharyngitis and/or adenitis. In between episodes, and even during the episodes, the children appear healthy. At least 6 months of episodes.
The study of the origins of the Palestinians, a population encompassing the Arab inhabitants of the former Mandatory Palestine and their descendants, [1] is a subject approached through an interdisciplinary lens, drawing from fields such as population genetics, demographic history, folklore, including oral traditions, linguistics, and other disciplines.
G2A in humans is encoded by the GPR132 gene. [6] [7] The G2A gene is located on chromosome 14q32.3 codes for two alternative splice variants, the original one, G2A-a, and G2A-b, that consist of 380 and 371 amino acids, respectively; the two receptor variants, when expressed in Chinese hamster ovary cells, gave very similar results when analyzed for functionality. [8]
John Peter Bain (8 July 1984 – 24 May 2018), better known as TotalBiscuit (/ ˌ t oʊ t ə l ˈ b ɪ s k ɪ t / TOH-təl-BISS-kit, TB; sometimes The Cynical Brit or TotalHalibut), was a British video gaming commentator and game critic on YouTube.
It is an immediate descendant of G2a (G-P15), which is a primary branch of haplogroup G2 (P287). G2a1 has an extremely low frequency in almost all populations except parts of the Caucasus Mountains. In 2017, the SNP L293 was replaced by FGC7535, SK1106 and Z6552 as the defining SNPs of G2a1, due to the technical difficulty in testing for L293. [1]
It is an East Asian haplogroup. [3] Today, haplogroup G is found at its highest frequency in indigenous populations of the lands surrounding the Sea of Okhotsk. [4] [5] Haplogroup G is one of the most common mtDNA haplogroups among modern Ainu, Siberian, Mongol, Tibetan and Central and North Asian Turkic peoples people (as well as among people of the prehistoric Jōmon culture in Hokkaidō).
The London and North Western Railway (LNWR) Class G2A was a class of 0-8-0 steam locomotives. They were upgraded from LNWR Class G1 principally by the fitting of a higher pressure boiler . Some of the G2As subsequently received lower pressure boilers on overhaul, taking them back into Class G1.
Paris 2024 Organizing Committee President Tony Estanguet unveiled the Olympic and Paralympic medals for the Games in February 2024, which on the obverse featured embedded hexagon-shaped tokens of scrap iron that had been taken from the original construction of the Eiffel Tower, with the Games' logo engraved into it. [18]
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