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Amphetamine is a weak base with a pK a of 9.9; [20] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich cell membranes of the gut epithelium. [20] [87] Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is ...
[18] [20] In the 1420s and 1430s, Cuauhnáhuac and Xiutepec were conquered by Itzcoatl. [20] In the middle of the 15th century, other city-states in Morelos made war on Aztec-held Cuauhnahuac and the Aztecs used this as an excuse to conquer areas such as Yautepec, Tetlama and other locations, eventually dominating the entire state.
Also then, Maniu was voted in as chairman; Mihalache, Lupu, Vaida-Voevod and Paul Brătășanu were vice presidents, while Madgearu became general secretary and Mihai Popovici cashier. [20] From October 17, 1927, the party central organ became Dreptatea , though the party continued to publish various other periodicals, including Patria . [ 21 ]