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Some 25% of out-of-pocket spending by individuals is for prescription drugs. [283] Another study finds that between 1990 and 2016, prescription drug prices in the US increased by 277% while prescription drug prices increased by only 57% in the UK, 13% in Canada, and decreased in France and Japan. [ 284 ]
[19] [20] The Earth's water cycle. About 97.5% of the water on Earth is saline; the remaining 2.5% is fresh water. Most fresh water – about 69% – is present as ice in ice caps and glaciers. [21] The average salinity of Earth's oceans is about 35 grams (1.2 oz) of salt per kilogram of seawater (3.5% salt). [22]
[20] In D/s, the dominant is the top and the submissive is the bottom. In S/M, the sadist is usually the top and the masochist the bottom, but these roles are frequently more complicated or jumbled (as in the case of being dominant, masochists who may arrange for their submissive to carry out S/M activities on them).
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