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Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ( CRISPR )- Cas9, transcription activator-like effector nucleases ( TALEN ), meganucleases, and zinc finger nucleases (ZFN). [1]
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A growing number of Israelis - nearly 50% - support an end to the Gaza war in exchange for the release of hostages - a view that was extremely rare in the weeks, if not months, following the Oct ...
Off-price is a trading format based on discount pricing. Off-price retailers are independent of manufacturers and buy large volumes of branded goods directly from them. The off-price retail model relies on the purchase of over-produced, or excess, branded goods at a lower price, thus being able to sell to consumers at a discount compared to ...
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History Early history. The hypothesis of dark matter has an elaborate history. In the appendices of the book Baltimore lectures on molecular dynamics and the wave theory of light where the main text was based on a series of lectures given in 1884, Lord Kelvin discussed the potential number of stars around the Sun from the observed velocity dispersion of the stars near the Sun, assuming that ...